Polyoma BK Virus: An Oncogenic Virus?
نویسندگان
چکیده
منابع مشابه
Polyoma BK Virus: An Oncogenic Virus?
We report a case of a 65-year-old gentleman with a history of end stage renal disease who underwent a successful cadaveric donor kidney transplant four years ago. He subsequently developed BK virus nephropathy related to chronic immunosuppressant therapy. Three years later, misfortune struck again, and he developed adenocarcinoma of the bladder.
متن کاملFrequency of BK Polyoma Virus in Bladder Cancer
The BK virus a member of the Polyomaviruses family was first isolated from the urine of the kidney recipient. Infection with this virus and infection usually occurs in childhood (5-9 years) but most of the time (90%) of sera are positive and without symptoms. Polyomaviruses including the BK virus have also been suggested to be a contributing factor to some cancers in humans such as brain tumors...
متن کاملBK virus nephropathy and other polyoma virus infections.
Polyomaviruses are mammalian (and a few avian) viruses, which appear to have coevolved with their hosts, leading to high prevalence, low morbidity, latent infections for the most part. The viruses generally have a restricted host range; 5 polyomaviruses are known to naturally infect humans (Table 1). Among them, BK virus is the most commonly encountered clinically, causing nephropathy, hemorrha...
متن کاملThe local oncogenic response of hamster tissues to polyoma virus.
culture preparations infected with the polyoma virus has not been determined. There is some evi dence that the tumors follow parasitization of host cells by the virus (8, 10), but the oncogenic re spouse may be the result of a very complex inter action between host and virus. In most experi ments massive doses of virus-tissue culture inocula have been used that initially permeate nearly all tis...
متن کاملPolyoma BK virus: an emerging opportunistic infectious agent of the human central nervous system.
BK virus, a double-stranded DNA virus, is a member of the Polyomaviridae family which is known to infect humans. Clinical evidence of disease is mostly encountered in immunosuppressed individuals such as AIDS patients or those who undergo renal or bone marrow transplantation where complications associated with BKV infection manifest commonly as a polyomavirus nephropathy or hemorrhagic cystitis...
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ژورنال
عنوان ژورنال: Case Reports in Nephrology
سال: 2013
ISSN: 2090-6641,2090-665X
DOI: 10.1155/2013/858139